2018/02/20@ʑ̐EXV܂B

FDCa

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{͂͂ecb̎aÂ𗝉邽߂ɕKvȈÏ𒆐Sɍ\Ă܂B̂ߎaɊւʓIȕa_͑̂goɑfڂĂ܂̂ŁAQƉB܂A_AזEԃVOi`BȂǂɊÂaȂǂ͐I܂̂ŕʂ̏͂ł킩₷`ŏ񋟂ƍlĂ܂B ł͂ecb̎aÂ̍lƎËZpB

PDa̕a

PDPDãoNeAgD̖ƉuDʂɂĂΎa͎n܂

a͎gDt߂ɑ݂a(oNeA)gD̖Ɖu͂苭ꍇɂ͔a܂BgD̖ƉuőOj΃oNeAgDɐNAgD\j󂷂邱ƂɂGlM[lB͂߂Ԃâ͂܂łB

Pj{HPł͎aAuނvAq͉ȂǂNȃ̂oNeAƌď̂܂B

PDQDa͋ǏłȂSgԂvAłΕa󂪐is

Aa͎gD̍\Ɖu͂̋AoNeÄxƂǏIȗvłȂAbA邢͒̃XgXȂǂ̉e邽߂舫܂B

QjbEEEƂČtiǁjӂȂǂɊ֘ASg̎ōAAaȂǂASsSAdNJ̏QAtsSAPai[}`jȂǂ̕aC

PDRDa͂SOˑ䂩{iIɐis

ɎaȂ璷̃XgXɔĂ钆N͑̕Sg̖Ɖu\͂͂STˑOォ}ɒቺ܂̂Łux̍oNeAv|PbgɔɐBĂ܂Ƌ}ɕa󂪐isꍇ܂BC‚Ǝ̎͂猌^ł邾łȂɂ݂ꂪAтL悤ɂȂ܂B

PDSD芪Ă鎕̔l͎𑁂

ɉ܂Ǝ̎͂̍ij̏ꍇAO{ɋߐڂĂ{̉PȂǂł͎xĂ鍜̕aIjɂĎꂽɂ񂾂肷邾łȂiƎ̓h傫ȂA̐l葁r܂B

QDȁǏ

QDPDa͎̕aCł͂ȂB

aɂoȂǂ͒ځÅŊmF邱Ƃł܂AꂪǏׂ̂Ăł͂܂BAaƂâ߂̕aCŁA͂₭fΎaɂȂȂƂFs⑊ɐisaɂ炸ubVOłȂAȂǂƂ悤łB
e|P

yadǂɂȂƃubVOł́Â悤ɏỏP݂͂ꂸAoNeA̐iEŁEjƃ[U[ÂKv















LAdǂ̎ã|Pbg̎悳ꂽʂrodT.ہB

QDQDa̕|͎̂x鍜nď邱

a낵̂́AłɏqׂĂ܂悤ɋCÂȂɎ̎͂̎ỉɑ݂jj󂳂ďĂƂłBxĂ鍜̂ł玕‚ď\Ɋ߂ȂȂ邾łȂŌɂ͎XƎĂ܂܂B

QDRDSgԂvAAgD̖Ɖu͂アꍇ͎Í

a̓ubVOŎ悤ȊȒPȕaCł͂Ȃ̗vɂĐ銴ł邽ߊ̎Ö@ł͏\ȉP߂ȂǗ܂BȂAecbÖ@͌q܂B

ȉɒxȏ̎a̕aЉv܂B

RDȁǏix`dǗj

R\PDȁdlj͐ĝُ̈펖

ȉɎa̕aƏǔʂȂǂĂ܂xdǂɓΌ݂̎a̎Ö@ł͖SȏԂɂȂĂ邱ƂɂȂƎv܂B̂Ƃ͎gDɌ肵×_ł͌E邱ƂĂ܂B

ȂƂΌogD͐ĝōł̎̑gDłAdvȓɑ݂邱ƂłBꂾɃoNeÂ悤ȐĝɗLQȈٕNh߂ɏ\ȖhVXe菄炳QSԋ@\Ă͂łB ɂ炸AȂAĝAdvgDɃoNeȂBĂ̂AƂƂłB

Ɖu͂ogDɃoNeAB‚Â̍aIɔj󂷂̂͋ɂ߂ĈُȎԂłB ł͈ȉɏǗȂ玕aÂ̖_Ƃecb̎gݕЉv܂B

R\QDaÂ̊{ƌEւ̒

PjǂƂẴoNeA΍́H

aǂł邱Ƃ͎łAȂɂD悷ׂƂ͌ƂȂoNeA̐inہEjłB ܂Aȃϐۂɑ΂ẮAOA|{ȂǂɂăoNeA̓ɉuזEj@v𒆐SƂ@EJĂ܂B

QjgD̖Ɖu͂͌̎aÂł͏\ȃRg[łȂB

ɁA]̎aÂȂĂeՂɃoNeAAĂ錻玕gD̖Ɖu͂ቺĂƍl܂BɂƉu͂̒ቺ͓RƂāAɏqׂ悤ɐSg̃vAȏԂ͖Ɖu͂ቺ܂BAa͂ߊbɂełȂAɎgp܂ev܂BtƂ̘AgɂẢۑɎgޕKv܂B

^̗͂Ɩhq̗́iƉúj͈قȂB

Rj̑lƕaIωɑ΂V_iƉuwj

܂A芪Ă鍜̗ʂ▧xlɂđ傫قȂĂȏAecbł͕ʃgQłȂCTBeɂđ玕a늳̐isXN\Ă܂B͂̎̏Ԃlɒ^uȂĂÌʂɂ͂Ȃ܂BɁA̕aIω͏]̖Ɖuwł͉łȂ肪܂̂łecb͐VlƂāuƉuwv̎_̌߂Ă܂B

SjXgXƎa

aa̖∫炷̂ł͂ȂAl͐EƒȊOɂʎ̂kЂȂǂ̑̃XgXɓXAĂ܂B̃XgXSłȂĝɉe邱Ƃ́u_ƉuwIvɂF߂Ă܂B

aȂƂXgXݐς̉eɂƉu͂̒ቺŕa󂪐iŝł玝aɉ̉e܂ʼnΕä͓RƂ܂B̏Ǐɑ΂Ăecb͏HÖ@ɓmwґz@ɂĉPv܂B

ȏAqׂ܂悤Ȏa͑lȗvݍAx܂Őis܂Ə]̒^uł͊ȒPɂȂȂaCł邱Ƃ肢ł傤B邱Ƃ́uoNeA͐Sgُ̈ʂvƂƂłB

Axȏ̏ǏłĂoNeAinہEjƓmwȂǂ̑ֈÂ邱ƂŎɂ݂ȂǂA܂͌yvaPv܂Be|TDPAe|TDQ

e|PDUV˂ŌSȎgD
iecbyIANeBuǗZpɂj

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e|RDʂ̏o

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u|PD|Pbg̃oNeA

e|SDr^iʁj

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e|TDr^iʁj

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e|UD

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e|VDт̗

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e|WDj󂳂ꂽbs摜

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e|XD

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e|POD

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͏]̎ÂȂ̂łAcoNeA̍ĊJɂǏ󂪈A@ɓ]シx̂ߔ̂łB

e|PPD̑r

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TV˒jiȂjF̈@Ŏfa͉PA^wEwaȂɂĎOȎpitbvIyj󂯂Rڂ̎pAیǂ̂ߑ̒sǂɂȂ肩‚̓ȈhN^[XgbvƂȂA@ɓ]BfAłɑ唼͕̎ۑs”\ȏԂɂAʑDNAɂĂʂ̃oNeAoꂽB

łɎ̕ۑ͍ł葁̔߂邪ӂȂ߂ɃoNeAinہEjA[U[ÁAHÖ@Ȃǂɂ艊ǏǏANĔsȂ́B҂Ɏa͂ȂƂałoNeAȃiKŎ{ĂȂꍇAɎOȎpȂĂÂ悤ȌʂɂȂ܂B

SD҂̎Ȑff

R|PD̏o͐ԐM̓_

̏oꍇ͕KʑɂoNeAKvłBoʂ̎|Pbgɂ͊AŐ̋ΐCۂ݂Ăꍇ܂B̂悤ȏꍇ͕aisȂ߂ɁAɁA|Pbg̃oNeA𐧈inہEjKv܂B

̎̃VOi߂Ă܂܂ƕa͂ɈĂ܂BɒN̏ꍇł͕a̐isɂ‚ĐԂo^ɕω܂̂ŋCÂɂȂ܂B

̂ߎa悤Ɋ܂ۂ͈iƈĂ܂B̒iK̃VOi͒ɂ݂⎕^ł邾ȂAt˂΂茙ȌLgU悤ɂȂ܂B

R|QD̓h͐ԐM

aff͎̏ԂA猩ȂƂ܂Ă鎕̕aIω𑁊̒iKŐmɐff邱ƂłdvłibsBeKvjBł̒ӓ_͎̓hłB^o邾łȂA΂ΎĂ悤ɂȂƂłɏdǂɂȂĂ܂B̃VOi𖳎ĂƉ̉eA‚̂܂ɂa󂪋}ɐis̎r܂B

PjʂɂȂ鎕|Pbg̑̓oNeAgDɗ^aIω̌ʂ𑪒肵Ă܂BmȐff̂߂ɂ́ǍʂY݂Ă錴̃oNeAo邱Ƃ挈łBÑO̎|Pbgɂ̓oNeAʂɑ݂Ô\邽߁Aɒɂ݂ꂪ郊XN܂B

QjC̃bhsDۂ͕qȋێ̂ߔ̑xł͕⑫邱ƂłAubVOtVOł邱Ƃ̂߃oNeAϋɓIɎEŁE鏈uKvƂȂB

TDÂ̗v_

S|PDmȐff

mȐffɊÂāA͂߂ēK؂ȎÂs邱Ƃ͂܂ł܂B̂߂ɂ͊ǂ̎ałΌƂȂoNeAȂƂɂĕãoNeAv܂BɊÂēK؂Ȏ”\ɂȂ܂B

S|QDȁu͐vAWIɎs

Â͑傫Ĉȉ̂Rۑ邱ƂłByǂ̏ꍇ͈ȉ̂PCȐuōς݂܂AxȏA‚܂莕̂P^Q܂Ŕj󂳂A̓h݂ꍇ͂P`R܂ł̏u𕽍sďWIɍsKv܂B

ȂAecbł̓oNeA𒆐SɃ[U[ÁAmwuAHÖ@Ȃǂ̑IȎÖ@ɂ莕aPĂ܂B̂߁A݂ł́Aقǂ̗O҂ɂƂĐgׂ̑̕傫OȎp͈ȑOقǕKvȂȂĂ܂B

  • PDoNeAinہEj

    ΐCۂ͂ߊeێ̐ɑΉoNeAinہEjs܂Ba͊ǂł̂ŎÂ̊{̓oNeAɂȂ܂B oNeA

  • QDhɑ΂𚐗͕Uȗ

    ̓hꍇ̓oNeA|Pbg[ɐN邽߁Ah߂ɓhŒ肷Kv܂BÒ̓ȟŒ̓oNeA̐[Nh~̂ř𚐉񕜂̂߂ł͂܂BVDaɂ铮h̎

  • RDaIgD̏C

    gD̑gD񕜂̂߂ɂ́Â܂ɂȂ󎀑gD̏oNeAɂĎYA~ςꂽ׋ۓłgD珜Kv܂B唼̓[U[Âŏ\łdǂ̏ꍇ͎OȎpKvłB

S|RDecbÖ@ɂP

ecbËZp͎a]̂悤ȎpRۍ܂ɗ炸A@oNeAinہEjAA[U[ÁABh̕Syu@@CaIgD̉PȂǂ̗lXȃnCeNZpⓌmwg邱ƂɂčDʂɓĂ܂B ȉɂecb̎×܂B

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UDFDC̐ff@

T|QDcm`iPCR-Invader@j

ecb͈ʑɂăoNeA̐Ԋώ@ȂĂ܂A2002N6cm`iPCR-Invader@jpĎ|Pbgɑ݂ĂoNeA̋ێې𕪗ށAʉĂ܂BuɑP̂cm`{A|Pbg̋ێAېL^AQڂ̌lƂ̑r΃|Pbg̃oNeȀԂqϓIɔf邱Ƃ”\ƂȂ܂BɁAÏp̎Ìʂ𔻒肷邱Ƃł܂B܂Al̑׋ېiΏۋۈȊO܂ށj犳҂̖Ɖu@\̋𐄒肷邱Ƃ”\łB

aL͈͂ɂԏꍇdǂ̏ꍇɂP̌ʂIɂ͐TdɍsȂKv܂B̏ꍇAʑA邢͂bs摜ȂǂƕđIɔf܂BȂAecb̂cm`ێ͗ՏoȉɎTێΏۂƂĂ܂BڂS|RDcm`͎Â̓oR

yΏۍ׋ہz
Prevotera Intermedia, Fusobakuerium nucleatum T.forsythensis, Prophronas.gingivalis,
A.actinomyscetemomitans,
jTreponema.denticolaȂтɈړ͈̂ʑŏ\ƍlĂ܂B

ycm`̗lqz
|Pbĝcm`̓|PbgɌyy[p[|CgPObԑ}邾ł̂ŁAɂ݂͂܂

T|RDcm`iPCR-Invader@jɂ‚Ă̂p`

pPD cm`iPCR-Invader@j̖ړÍH
`PD a̐ff⎡Ìʂ̔f[^ƂĎgp܂B|Pbg̃oNeA̎ނʂ𐳊mɒׂ邱Ƃɂff̐xコ邱Ƃł܂B
pQD cm`iPCR-Invader@j͂‚H
`QD ecb̌2002N6łB
pRD ʑƂ̈Ⴂ
`RD ʑ̓oNeA𐶂܂܊ώ@邱Ƃł܂Bꂪ̌Ƒ傫ȈႢłB̂߂ɃoNeẢ^␶ۂۂ̔ʁA邢̓oNeA̖xȂǕaɑ݂oNeÃ_Ci~bNȐԂώ@”\łB

Acm`ł̓oNeA𐶂܂܊ώ@邱Ƃ͂ł܂񂪈`q͋ZpŃoNeA̖Omɔ܂B܂A܂Aې𑪒肷邱Ƃł܂̂ŁAqϐ̍ÂsȂƂł܂B
pSD ͂ǂ̗lȏǏɂȂΎ󂯂Kv܂H
`SD ȓIȕaCȂ̂ɂ炸̏oz[PAŎ~Ȃ悤ȏꍇȂǂ͕Kv܂B
pTD ͂PxłH
`TD ͏pOAp̂QKvłBAecb͈ʑ̂PUOOÕf[^x[X܂̂ŏ̎a͈ʑŗՏ̖薳AƍlĂ܂BAAǗႠ邢͎OȎp͕KvłB
pUD ṕH
`UD ݁A͂UێłQWCOOO~łBhCcł͌NیɂPON炢O瓱Ă܂{ł͕یɓKpĂ܂BAcm`邱ƂɂImȐff܂̂ŒNɂȂĎrACv`ɂȂ邱ƂlΕKvȌNƂ܂B

ycm`iinvader@jʁ@Pz
cm`iinvader@jʒʒm[B

ycm`iinvader@jʁ@Qz
cm`iinvader@jʒʒm[B

to be continued