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ҏ\グ܂BĊxf̂m点

@WPRij`PTij

EEgEt@Couiteajɂ鏜ۖ@^pJn

RDecb̎ÌXVB

SDPoNeAiaj̕Kv

S|PDȂAecb̎Â̓oNeAd̂H

厕Ȏ́uvƎa͊ǂłuff_Ǝ×_v\z邽߂ɌłoNeÁuoNeAvSɂȂ܂BÂ悤Ȋ_ɊÂՏsׂsȂȂꍇ͍ĎÂłȂAیǁiOdontogenic bacteremiajɂĐl̂̏Ɉe^܂BkPDQDRDl

ɏhiqgj̖ƉuVXe̓oNeȂgDɐN邱Ɩhq@\SĂ܂BAłɔnjB⎕gD̕aIj󂪎n܂ĂiKł͖炩ɖƉu@\ቺĂ邩A邢͒ʏ̖Ɖu@\鋭͂ȃoNeÅ肳܂BŃoNeAɂãoNeA̎ނ␶ԁAɑgD̖Ɖu@\̏Ԃ̓Iɒm邱Ƃ”\ɂȂ܂B

̗RecbÂɂăoNeAdӖՂƎv܂B

ǎÂ̓oNeAɂ͂܂AoNeAɏIB̂ɃoNeAȂĎÂȂB

yRefferencesz

  1. Stepanovic, S., T. Tosic, B. Savic, M. Jovanovic, G. K'Ouas, and J. P. Carlier. 2005. Brain abscess due to Actinobacillus
    actinomycetemcomitans. APMIS 113:225-228.

  2. Novak, M. J., and H. J. Cohen. 1991. Depolarization of polymorphonuclear leukocytes
    by Porphyromonas (Bacteroides)gingivalis 381 in the absence of respiratory burst activation. Infect. Immun.59:3134-3142.

  3. Wagner, K. W., R. Schon, M. Schumacher, R. Schmelzeisen, and D. Schulze. 2006. Case report:
    brain and liver abscesses caused by oral infection with Streptococcus intermedius.
    Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 102:e21-e23

S|QDoNeAŽȂΐłȂ

^[QbgiڕWj߂邽߂ɂ͊҂̎|Pbguނv|ɁA@ǂ̂悤Ȏނ̃oNeAAAǂ̒x݂ABǂ̂悤ȐԂȂ̂AA^CɌ邱ƂoȂ΂Ȃ܂B̖ړÎ߂ɁyoNeA𐶂܂܉Žłzʑ͕sŒłB

ɎۂɂȂ܂A萳mɃoNeAl錟@Ƃāycm`ih@jz܂Bcm`̓oNeÅӕʂƒʉ”\ł̂ňʑƂ͈قȂ_̃oNeAm邱Ƃł܂Becb͓fÂɁÂQނ̌@oNeÃc[ƂĂ܂B

S|RDcm`͗Lȃc[ߑ]͋֕

cm`ɂĎ|Pbg̃oNeA̎ނoNeA̒ʉ”\ɂȂ܂̂Őffx͈iƌサ܂BAՏ̖_ƂĂ͌ΏۂێɌĂA܂ʂ̓^CO邽ߌ̕aɂ́Aނ̃oNeAAꂮ炢݂Ă܂AƂߋ̃oNeAɂȂ邱ƂłB

ɖ݂͌̂cm`񍐏ł͂oDہAsDۂƊeXPނ݂̂\LĂ܂BAۂɂ͎âoDہio@j͂PXA܂sDہis@j̏ꍇł͂PV푶݂Ă܂B̂߂sDۂ̕ނł͍Rۍܑϐ̂sDۂAۂ̋ʂł̂Őx̍Âɂ͕s\Ƃ܂B

sDۂ̗̂悤Ɋ{\͋ʂĂĂRۍ܂ȂNJỎeɑ΂@\ƂȂuψًہv݂Ă܂@B̂悤ɂsDۂoDۂ̗łlȕψق݂܂̂łecbł͂cm`Ƃǂߑɕ]邱ƂȂʑȂǂ̃oNeA𑍍IɍlȂff⎡ÂɓĂ܂B

S|SDoDۂ͂Pł͂Ȃ

PjoNeA͐i

L̕\is|Pj͌oɑ݂SEW߂ăXgbNĂłM̂HOMDig @n@la@Database(Forsyth Institute.USA)yoDہzɂ‚Ĉp̂łB̂悤P.gۂƌĂPł͂Ȃ݁A`q\̈قȂ̂͂PXi2016D10D30D݁jɂȂĂ܂B

oDۂPXޑ݂ƌƂ͊‹ωɑΉČ‘̂̐߂邽߂ɃoNeA̍\@\ȂǂîƐ肳܂B

jis|Pjł17̋LڂłA݂19ɑĂ܂B

QjoNeÃEB[N|Cg𕪐͂

oNeÂ悤ɐiȏAɃ^[QbgiڕWjɂoNeA̍\␶Ԃ̕ωɊւVmĂƂ͎Ðp̏ォKvɂȂ܂BႦ΂oDۂmɐinہEjĂ߂ɂ͂oDۂ́y^pN\zyA~m_zz܂ł̍ŐVf[^x[XOIɎWv܂B

WꂽyoNeAzɂĂoDۂ́uoNeA̍\vuӃVXevA邢́uNIZVO\́vȂǂ̃EF[N|Cg‚oƂ”\ɂȂ܂B̌ʁAÌʂ߂邱Ƃ”\ɂȂ邾łȂyoNeAzWIɉ^pł܂B

S|TDoNeA̕qwI̓

ecbł͐mȐff⎡Ðтコ邽߂ɂ͊҂́yGzłoNeA𕪎qwIȃxō\@\̏肵AՏɐƂƍlĂ܂BȂȂAՏŐ키̃oNeAQ͌Ŕ|{ꂽVHWہAP킾ł͂Ȃ2N5疜NȏAnł̊@ToCoĂ쐫̑lȃoNeAWcłAƂƂłB

̑lςȃoNeAɑ΂ăp^[̎ÂRۍ܂𗊂Ă邾ł͗ՏƂ͕ψقJԂɏɎ哱As{ӂȎÌʂɂȂ܂BoNeAɏ‚߂ɂ͓OꂵăoNeA̍\@\̎_nmAɍUiWȂ΂ȂȂƍlĂ܂B̎i邽߂ɂ́A܂oNeA̕qIȏ񂪕KvɂȂ܂B

ł͂oDۂ̗ō\B1‘̂̕Gȍ\ƃJjYɋł傤B

ȂAȉ̐ɎgpĂ}\̓tH[TCXičĵglca猟AgpĂ܂B These charts used in the following explanation were searched from HMDB (Human Microbiome Database) of The Forsyth Institut (USA).

s|PD

oDۂPVi݂͂PXj
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cm`ɂĂoDۂӕʂ邱Ƃł܂݁AoDۂ̒Ԃ́us|Pv葽PXiQOPUDPODROj݂Ă܂BoDۂƂĂ̊{Iȃ^pN\ӂ̃JjYLĂ܂Aꂼ`qxł͂낢ȕω݂܂B

Ⴆ΁yrdp@hcQUPUẑoDۂ͐擪̃A~m_ThreoninełAyrdp@hcQTOVẑoDۂłAlanine擪ɂȂĂ܂B́Aق̈ꕔłoDۂłĂÂ悤ȍ\ɍ܂ƂlhbinہjsȂꍇɂ͈قȂʂ”\l܂BAecb̐uɂĂꕔ̌ʂɂ͍܂B

jis|Pjł͂oDۂ17̋LڂłA݂19@

s|QD

oDۂ̂ς\iꕔj
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s|QD͂oD (ꕔ)̍\Ƌ@\Ɋ֌W^pNLqĂ܂B\̉E[iGene Product Namej̊esɂ͂oDۂ́u\p[cvuyfvȂǂ̃^pNLڂĂ܂Bۂ̂oDۂł͎ނɂÂ悤ȃXgPXOO`QROOsɂ킽ċLڂĂ܂B

ӂׂƂ́ÃXg̒ɂ@im@\ςjƂ@\łȂςUx܂܂Ă܂B݁Ã^pN͂oDۂ̒ŁAǂ̂悤Ȗʂ̂słBʂɂ悭mĂoDۂłA܂𖾂ĂȂ@\܂B

j@i@\mςj闝R̓Qm񂩂琄肳^pN̋@\߂ÂɃA~m_ꎟ\̑͂炨ȂĂ邩łBo銈wWƂāAɑΉ`qIVXeɂ^pN𕪗ނ@]܂B

s|RD

oDۂ̃RhXĝPĂ܂B
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s|RD͂oDۂDNARhA~m_𐻑郋[܂B\̍[̉Ɂyfffzƕ񂾋LÃRhŃA~m_́ufFOVi̍sQƁjv‚܂B܂AÉׂy`sbźyhFC\CVzɂȂ܂B̂悤Ɋj_̃Rh炔qm`̓ɂăA~m_𐻑AɃA~m_`G[ĂoDۂɕKvȃ^pNo܂B

oNeA̓~NTCYPȍ\Ǝv݂łBAۂ͋ȃVXeɂĉғ鉻wHBłB

PDEBMiEvidence Based Medicine)ɕKvȃoNeA

ǂ̂ނ⎕a̎Â𐳊mŌIɐi߂Ă߂ɂ͈ʑ ɂăA^CɕãoNeA̎ނƊ Kv܂BȊẘ(ʑjɂĊloNeA ÂÂȊwIEBMƂ܂B

QDoNeAɂ鐳mȐff

ႦΏo𔺂dǂ̎ȁꍇAoNeǍʁAT.d Ɣ܂ƁA̋ۂɗLȍRۍ܂𓊗^邱ƂɂAoȂȂ莕 gD}ɉP܂B̂悤ɃoNeAɂď]͌o Z\ɗĂȎÂ𕁕Ր̍Âɐi邱Ƃł܂B

RDubVOoX̃oNeA}~ʂ̔

R|PDoqObY͉Ԑ

ނ⎕ãubVO@͈ȑOlXȏplĂĂ܂B ܂Aŋ߂ł͂ނ⎕ałȂ̌L֌Wɂ鑽lȗ\hObYoX̂blpɂɗAł̓X[p[ʔ̂łȂƓdɂĂFƂǂ̏iׂĂ܂B
A\hObYɂ\hʂ͂ǂ̒x̂ł傤H

R|QD}ChRg[̖ڊo

Ⴆ΁A܂ŌoX͂̃G`Pbgx̗pƂĐ`Ă܂Aŋ߂ł͈ʂ̐lX̓oNeA邱ƂłȂƂɂ‚݁Aނ⎕aۂɑόʂ悤ȃC[WblȂĂ܂BʂāA܂ňȏɗ\hʂ͂̂ł傤Hecb̗܂Ǝaŗ@ꂽ҂Ƀz[PAɂ‚Ďf܂ƂAiNoXpԈႢȂɌʂɂƎ咣Ă܂B

AʑŌ܂ƕΐCۂ͂A̋ۂɑ΂ĂoNeA͖͂wǂȂƂ܂B͖̎{CŁIƂPTԂƂgpAČ܂ʂ͂܂łB܂ł̓R}[VMĂꂽ҂AɂQ̌ʂɂă}ChRg[oꂽ悤łB

R|RDoXɂ\hʂ̕]

̗͍ŋ߁AꂽoXłAނۂłȂaۂɂʂƂ̂Ƃŏixɂ͖^w̖OYtĂ܂BāAoNeAɑ΂錋ʂ͂ǂł傤Hȉ̉摜B

u\PDXgp̌

oXgpASԌo߂̉EPP̎|Pbg̎悳ꂽ

u|QD̏ɌoXH

̂ɌoXPHAAIώ@AR̈ʑ܂Biۂɂ͂RԂꕔʂX邱Ƃ͍lȂj@Ha\hɂ́Ã^CṽoNeAގKv܂B̊҂̌̂ľʂłĂ܂Bĉ摜ʂ\hʂ̔͂ł傤

u|RD̂ecblhb@iȈՖ@jŏ
ʂłB

̎悳ꂽ̂łȂAP̎|PbgɂKp܂lɃS~̂悤ɂȂoNeA̋ۑ̕ioNeA̎́j݂܂BoNeA̐‹\luΓŘʂłB

u|SDoX̓et

摜͗e悭UhaꂽXt̂łBłɎۂ݂Ă܂B̌ʂ݂ƂQ‚̋^₪܂B

Pjnt̔A̐ʁi_Nۂ̐iRHjʼnʂČʂ̂H

QjĂۂA̗ê܂ܓXɂāA@ǂ̒x̊ԁA@\ۂA”\Ȃ̂H

jۂł͌ʂ҂łȂ͂B
‹ł͌ʂ̂܂񂪁AiƂĂ͋^₪c܂B

Ĉȏ̌摜ʂ\hʂ̔͂ł傤H

oXC[WD݂őI͎RłA̎邽߂ɖ{Cŗ\hʂ҂̂ł΃oNeAɂđI邱ƂE߂܂Bgp@HvΗLȌoX܂B

SDfËԂ⎡Êނ̖ŋہAŏԂ̊mF

ÂsfËԂ͋Ɍ܂ƃoNeAԂƂ܂B

ecbł͊h~̂߂ɂ͐fËԂ̋C␅͂AfÂŎgp鎡 Êނ̖ŋہAłsĂ܂BAIȃoNeAł sRȎ݂͂₩ɖŋۂŎ菇̃`FbNsłȂՎ̃oNeAsȂĂ܂B ꌩAɌfËԂłoNeAE`FbNsĂȂΈwI ͋^łB

łȂwIfËԂ̊{łB


ȏ̂悤ɊǐffEÂ\hł̓oNeAsŒłB